BDBM702229 US20240360137, Example 28

SMILES O=C1N([C@@H]2CCC[C@@H](O)C2)c2nc(Nc3c[nH]nc3-c3cnn4ccccc34)ncc2C12CC2

InChI Key InChIKey=DGWCCEJPIJAFAF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702229   

LigandPNGBDBM702229(US20240360137, Example 28)
Affinity DataIC50: 11nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702229(US20240360137, Example 28)
Affinity DataIC50: 1.18E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702229(US20240360137, Example 28)
Affinity DataIC50: 2.12E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702229(US20240360137, Example 28)
Affinity DataIC50: 2.54E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent