BDBM702231 US20240360137, Example 30

SMILES O=C1N([C@@H]2CCC[C@@H](O)C2)c2nc(Nc3c[nH]nc3OC3CCC(F)(F)C3)ncc2C12CC2

InChI Key InChIKey=JUIFNVJAGULPQN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702231   

LigandPNGBDBM702231(US20240360137, Example 30)
Affinity DataIC50: 22nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702231(US20240360137, Example 30)
Affinity DataIC50: 4.27E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702231(US20240360137, Example 30)
Affinity DataIC50: 6.95E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702231(US20240360137, Example 30)
Affinity DataIC50: 9.80E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent