BDBM702245 US20240360137, Example 44

SMILES COCC(F)(F)COc1n[nH]cc1Nc1ncc2c(n1)N([C@@H]1CCC[C@@H](O)C1)C(=O)C21CC1

InChI Key InChIKey=OTIFMGNCVABLHF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702245   

LigandPNGBDBM702245(US20240360137, Example 44)
Affinity DataIC50: 15nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702245(US20240360137, Example 44)
Affinity DataIC50: 1.81E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702245(US20240360137, Example 44)
Affinity DataIC50: 4.41E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702245(US20240360137, Example 44)
Affinity DataIC50: 7.13E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent