BDBM702269 US20240360137, Example 68

SMILES CSCc1n[nH]cc1Nc1ncc2c(n1)N([C@@H]1CCC[C@@H](O)C1)C(=O)C21CC1

InChI Key InChIKey=JLYOIUAGJWTNDC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702269   

LigandPNGBDBM702269(US20240360137, Example 68)
Affinity DataIC50: 7nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702269(US20240360137, Example 68)
Affinity DataIC50: 970nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702269(US20240360137, Example 68)
Affinity DataIC50: 4.15E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702269(US20240360137, Example 68)
Affinity DataIC50: 7.60E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent