BDBM702281 US20240360137, Example 80

SMILES Cn1cc(-c2n[nH]cc2Nc2ncc3c(n2)N([C@@H]2CCC[C@@H](O)C2)C(=O)C32CC2)cn1

InChI Key InChIKey=RUQRDDNNROXSLQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702281   

LigandPNGBDBM702281(US20240360137, Example 80)
Affinity DataIC50: 29nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702281(US20240360137, Example 80)
Affinity DataIC50: 6.01E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702281(US20240360137, Example 80)
Affinity DataIC50: 9.30E+3nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

LigandPNGBDBM702281(US20240360137, Example 80)
Affinity DataIC50: 1.00E+4nMAssay Description:Biochemical assays measured the inhibitory effects of compounds in this disclosure on the enzymatic activity of CDK enzyme in complex with Cyclin pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent