BDBM702287 US20240360148, Example 1

SMILES C=CC(=O)N1Cc2sc(C#N)cc2[C@H](c2ccccc2-c2cn(CC)nc2C(F)(F)F)C1

InChI Key InChIKey=LXXAVIIROWQWSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 702287   

TargetSUMO-activating enzyme subunit 1(Human)
Suvalent Therapeutics

US Patent
LigandPNGBDBM702287(US20240360148, Example 1)
Affinity DataIC50: 210nMAssay Description:Assay buffer was prepared [50 mM HEPES, pH 7.5, 0.1% BSA and 10 mM MgCl2] as was the Stop Buffer [100 mM HEPES, pH 7.5, 0.05% Tween20, and 410 mM KF]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent