BDBM702324 US20240360148, Example 50

SMILES CCn1cc(-c2c(F)cccc2[C@@H]2CN(C(=O)/C=C/CNC)Cc3sc(C#N)cc32)c(C(F)(F)F)n1

InChI Key InChIKey=LJAHFHAOAHVLNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 702324   

TargetSUMO-activating enzyme subunit 1(Human)
Suvalent Therapeutics

US Patent
LigandPNGBDBM702324(US20240360148, Example 50)
Affinity DataIC50: 510nMAssay Description:Assay buffer was prepared [50 mM HEPES, pH 7.5, 0.1% BSA and 10 mM MgCl2] as was the Stop Buffer [100 mM HEPES, pH 7.5, 0.05% Tween20, and 410 mM KF]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent