BDBM702345 US20240360148, Example 83

SMILES CCn1cc(-c2ccccc2[C@@H]2CN(C(=O)/C=C/[C@@H]3CC(C)(C)CN3)Cc3sc(C#N)cc32)c(C(F)(F)F)n1

InChI Key InChIKey=DWZRSIADHSXYDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 702345   

TargetSUMO-activating enzyme subunit 1(Human)
Suvalent Therapeutics

US Patent
LigandPNGBDBM702345(US20240360148, Example 83)
Affinity DataIC50: 760nMAssay Description:Assay buffer was prepared [50 mM HEPES, pH 7.5, 0.1% BSA and 10 mM MgCl2] as was the Stop Buffer [100 mM HEPES, pH 7.5, 0.05% Tween20, and 410 mM KF]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent