BDBM702514 US20240360154, Compound Z4-1

SMILES CC(=O)N1CC[C@]2(C1)Nc1c(cnc3[nH]cc(C(=O)c4ccc(Oc5ccccc5)cc4Cl)c13)NC2=O

InChI Key InChIKey=LVQWZNSCOWZPCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 702514   

TargetTyrosine-protein kinase BTK [C481S](Human)
Genfleet Therapeutics (Shanghai)

US Patent
LigandPNGBDBM702514(US20240360154, Compound Z4-1)
Affinity DataIC50: 6.80nMAssay Description:A 3-fold gradient concentration stock solution of 1000× compound was prepared using DMSO and diluted 100-fold to 10× compound stock solution using re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genfleet Therapeutics (Shanghai)

US Patent
LigandPNGBDBM702514(US20240360154, Compound Z4-1)
Affinity DataIC50: 17nMAssay Description:A 3-fold gradient concentration stock solution of 1000× compound was prepared using DMSO and diluted 100-fold to 10× compound stock solution using re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent