BDBM702557 US20240360154, Compound Z25

SMILES CO[C@@H]1CC[C@]2(C1)Nc1c(cnc3[nH]cc(C(=O)c4ccc(Oc5ccccc5)cc4Cl)c13)NC2=O

InChI Key InChIKey=WTOBIBFFQBZDII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 702557   

TargetTyrosine-protein kinase BTK [C481S](Human)
Genfleet Therapeutics (Shanghai)

US Patent
LigandPNGBDBM702557(US20240360154, Compound Z25)
Affinity DataIC50: 4.90nMAssay Description:A 3-fold gradient concentration stock solution of 1000× compound was prepared using DMSO and diluted 100-fold to 10× compound stock solution using re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genfleet Therapeutics (Shanghai)

US Patent
LigandPNGBDBM702557(US20240360154, Compound Z25)
Affinity DataIC50: 6nMAssay Description:A 3-fold gradient concentration stock solution of 1000× compound was prepared using DMSO and diluted 100-fold to 10× compound stock solution using re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent