BDBM702630 US20240360154, Compound Z79

SMILES COC[C@]1(C)Nc2c(cnc3[nH]cc(C(=O)c4ccccc4Cl)c23)NC1=O

InChI Key InChIKey=LNXWTTCXOBOKLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 702630   

TargetTyrosine-protein kinase BTK [C481S](Human)
Genfleet Therapeutics (Shanghai)

US Patent
LigandPNGBDBM702630(US20240360154, Compound Z79)
Affinity DataIC50: 3.20nMAssay Description:A 3-fold gradient concentration stock solution of 1000× compound was prepared using DMSO and diluted 100-fold to 10× compound stock solution using re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genfleet Therapeutics (Shanghai)

US Patent
LigandPNGBDBM702630(US20240360154, Compound Z79)
Affinity DataIC50: 5.80nMAssay Description:A 3-fold gradient concentration stock solution of 1000× compound was prepared using DMSO and diluted 100-fold to 10× compound stock solution using re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
US Patent