BDBM702975 US20240366807, Formula I.1

SMILES C[C@@H](NC(=O)c1ccc(F)cc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=WYMLESYSOOLFCH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 702975   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM702975(US20240366807, Formula I.1)
Affinity DataIC50: 220nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM702975(US20240366807, Formula I.1)
Affinity DataIC50: 260nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM702975(US20240366807, Formula I.1)
Affinity DataIC50: 4.10E+3nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM702975(US20240366807, Formula I.1)
Affinity DataIC50: 5.70E+3nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent