BDBM703029 2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- lidin-3- yl)butanamide Isomer 1::US20240368078, Compound 46

SMILES CC[C@@H](C(N)=O)[C@H]1CN[C@@H](c2c(O)ccc(Cl)c2Cl)C1

InChI Key InChIKey=QDTMMSZHUQYINK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703029   

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703029(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703029(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent