BDBM703038 2-((2R,4S)-4-((1H- pyrazol-3- yl)methyl)pyrrolidin- 2-yl)-3,4- dichlorophenol::US20240368078, Compound 55

SMILES Oc1ccc(Cl)c(Cl)c1[C@H]1C[C@@H](Cc2cc[nH]n2)CN1

InChI Key InChIKey=IWTHRUIADBJCFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703038   

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703038(2-((2R,4S)-4-((1H- pyrazol-3- yl)methyl)pyrrolidin...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703038(2-((2R,4S)-4-((1H- pyrazol-3- yl)methyl)pyrrolidin...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent