BDBM703441 US20240368109, Example 2

SMILES CCOc1ccc([C@@H](COC)NC(=O)C2C3Cc4ccccc4C32)cc1

InChI Key InChIKey=CMEXQSOCIXZGAX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703441   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM703441(US20240368109, Example 2)
Affinity DataEC50:  72nMAssay Description:Test compounds were assessed for their ability to modulate the function of the α7 nicotinic acetylcholine receptor both in the presence, and in the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent