BDBM703738 US20240368133, Compound A-215::[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)phen- yl]piperazin-1-yl]- (2-pyridyl)meth- anone

SMILES CC(C)Cc1cc(F)c(-c2nn[nH]n2)c(N2CCN(C(=O)c3ccccn3)CC2)c1

InChI Key InChIKey=QHEIPULNZCAKMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703738   

LigandPNGBDBM703738([4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)phen...)
Affinity DataIC50: 300nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent