BDBM704120 US12138263, Compound 7A

SMILES C[C@@H]6OCC5(CCN(c4cnc3c(N2CCCc1cc(OS(=O)(=O)F)ccc12)n[nH]c3n4)CC5)[C@@H]6N

InChI Key InChIKey=LJBDRQFXYNGUBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704120   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM704120(US12138263, Compound 7A)
Affinity DataIC50: 1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (S12) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2025
Entry Details
US Patent