BDBM704480 6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpholinoanilino)-5-(trifluoromethyl)pyrazine-2-carboxamide::US20240374606, Example 33

SMILES Cn1cnc2c(-c3nc(C(N)=O)c(Nc4ccc(N5CCOCC5)cc4)nc3C(F)(F)F)cncc21

InChI Key InChIKey=QAAPNQHOXOZPHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 704480   

LigandPNGBDBM704480(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandPNGBDBM704480(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 166nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

US Patent
LigandPNGBDBM704480(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 3.80E+3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent