BDBM704638 3-[4-(1,1-Dioxo-1,2-thiazolidin-2-yl)anilino]-5-(methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7-yl)pyrazine-2-carboxamide::US20240374606, Example 191

SMILES CNc1nc(Nc2ccc(N3CCCS3(=O)=O)cc2)c(C(N)=O)nc1-c1cncc2c1ncn2C

InChI Key InChIKey=XIMFQJJHFJVOJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 704638   

LigandPNGBDBM704638(3-[4-(1,1-Dioxo-1,2-thiazolidin-2-yl)anilino]-5-(m...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandPNGBDBM704638(3-[4-(1,1-Dioxo-1,2-thiazolidin-2-yl)anilino]-5-(m...)
Affinity DataIC50: 12nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

US Patent
LigandPNGBDBM704638(3-[4-(1,1-Dioxo-1,2-thiazolidin-2-yl)anilino]-5-(m...)
Affinity DataIC50: 1.27E+3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent