BDBM704703 3-Hydroxy-5- (3-m-tolylisoxazol-5- yl)picolinoyl glycine::US20240376089, Compound I-2

SMILES Cc1cccc(-c2cc(-c3cnc(C(=O)NCC(=O)O)c(O)c3)on2)c1

InChI Key InChIKey=VAFKRDGIENGMGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704703   

TargetEgl nine homolog 1/Hypoxia-inducible factor 1-alpha [788-822](Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM704703(3-Hydroxy-5- (3-m-tolylisoxazol-5- yl)picolinoyl g...)
Affinity DataIC50: 133nMAssay Description:The ability of the compounds to compete with a fluorophore-labeled HIF-la peptide fragment (FITC-HIF-1α 788-822) for binding to the PHD2 protein was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent