BDBM705301 US20240376119, Example 22

SMILES C=Cc1nc(Sc2cccc(-c3ncco3)c2Cl)c(N)nc1N1CCC2(CC1)Oc1ccccc1[C@H]2N

InChI Key InChIKey=BUHRZBAVRAMIPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 705301   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM705301(US20240376119, Example 22)
Affinity DataIC50: 20nMAssay Description:A mixed liquor of 2× working SHP2 reagent (0.4 nM) and 0.5 μM SHP-2 activated peptide (BPS bioscience #79319-2) was prepared with 1× enzyme buffer. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent