BDBM705305 US20240376119, Example 57

SMILES [2H][C@@]1(N)c2ccccc2OC12CCN(c1nc(N)c(Sc3ccnc(N)n3)nc1C(C)=O)CC2

InChI Key InChIKey=BXVWKMBROQUVAU-OKWSDYJOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 705305   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM705305(US20240376119, Example 57)
Affinity DataIC50: 20nMAssay Description:A mixed liquor of 2× working SHP2 reagent (0.4 nM) and 0.5 μM SHP-2 activated peptide (BPS bioscience #79319-2) was prepared with 1× enzyme buffer. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent