BDBM705455 2''-fluoro-5''-methoxy-6-methyl-N-[5-(morpholin-4-yl)- [1,3]thiazolo[5,4-d]pyrimidin-2-yl]-[4,4''-bipyridine]-3-carboxamide::US12145945, Example 93

SMILES COc1cnc(F)cc1-c1cc(C)ncc1C(=O)Nc1nc2cnc(N3CCOCC3)nc2s1

InChI Key InChIKey=HMAJMCPKHPIKME-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 705455   

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM705455(2'-fluoro-5'-methoxy-6-methyl-N-[5-(morpholin-4-yl...)
Affinity DataIC50: 100nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Polθ protein (P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent