BDBM705479 2''-chloro-5''-methoxy-6-methyl-N-[5-(2- oxopiperidin-1-yl)-[1,3]thiazolo[5,4- b]pyridin-2-yl]-[4.4''-bipyridine]-3- carboxamide::US12145945, Example 118

SMILES COc1ccc(C#N)cc1-c1cc(C)ncc1C(=O)Oc1nc2ccc(N3CCCCC3=O)nc2s1

InChI Key InChIKey=UBKDTBPAWYWXCA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 705479   

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM705479(2'-chloro-5'-methoxy-6-methyl-N-[5-(2- oxopiperidi...)
Affinity DataIC50: 100nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Polθ protein (P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/8/2025
Entry Details
US Patent