BDBM705482 2''-chloro-5''-methoxy-6-methyl-N-{5- [(2H-1,2,3,4-tetrazol-5-yl)methoxy]- 1,3-benzothiazol-2-yl}-[4,4''-bipyridine]- 3-carboxamide::US12145945, Example 121

SMILES COc1cnc(Cl)cc1-c1cc(C)ncc1C(=O)Nc1nc2cc(OCC3=NCN=N3)ccc2s1

InChI Key InChIKey=BHYVCKRVFMFTMK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 705482   

TargetDNA polymerase theta(Human)
Breakpoint Therapeutics

US Patent
LigandPNGBDBM705482(2'-chloro-5'-methoxy-6-methyl-N-{5- [(2H-1,2,3,4-t...)
Affinity DataIC50: 100nMAssay Description:The Polθ ATPase assay was used to evaluate inhibitors of Polθ ATPase activity, in vitro. Experiments were performed using a truncated Polθ protein (P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/8/2025
Entry Details
US Patent