BDBM70568 MLS000550969::N-(4-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-1,4-dioxo-1,4-dihydro-naphthalen-2-ylsulfamoyl}-phenyl)-ac etamide::N-[4-[[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-dioxo-2-naphthalenyl]sulfamoyl]phenyl]acetamide::N-[4-[[3-[4-(4-fluorophenyl)piperazin-1-yl]-1,4-bis(oxidanylidene)naphthalen-2-yl]sulfamoyl]phenyl]ethanamide::N-[4-[[3-[4-(4-fluorophenyl)piperazin-1-yl]-1,4-dioxonaphthalen-2-yl]sulfamoyl]phenyl]acetamide::N-[4-[[3-[4-(4-fluorophenyl)piperazino]-1,4-diketo-2-naphthyl]sulfamoyl]phenyl]acetamide::SMR000145097::cid_4261850

SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NC1=C(N2CCN(CC2)c2ccc(F)cc2)C(=O)c2ccccc2C1=O

InChI Key InChIKey=DDJAVDROWBVAEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 70568   

TargetCaspase-9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 70568BDBM70568(N-[4-[[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-di...)
Affinity DataIC50: 1.01E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2012
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 70568BDBM70568(N-[4-[[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-di...)
Affinity DataIC50: 1.74E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 70568BDBM70568(N-[4-[[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetTyrosyl-DNA phosphodiesterase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 70568BDBM70568(N-[4-[[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-di...)
Affinity DataIC50: 1.28E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay