BDBM706145 US20240383893, Compound 2

SMILES COc1ccc2c(Oc3ccc(CC(=O)NO)cc3)ccnc2n1

InChI Key InChIKey=DLTFWMDUGAOHIZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706145   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM706145(US20240383893, Compound 2)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ECD-his tagged human ENPP1 using 2',3'-cGAMP as substrate preincubated for 15 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM706145(US20240383893, Compound 2)
Affinity DataIC50: 1.90nMAssay Description:Preparation of 1×reaction solution: 50 mM Tris-HCl (pH 7.5), 10 mM NaCl, 0.5 mM CaCl2), 1 μM ZnCl2, 0.01% Tween-20, 0.01% BSA.Preparation of compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
US Patent