BDBM706244 US20240383893, Compound 110

SMILES COc1ccc2c(Oc3ccc(C(C)(C)C(=O)NO)c(F)c3)ccnc2n1

InChI Key InChIKey=XUPUTIXFVKXTNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706244   

LigandChemical structure of BindingDB Monomer ID 706244BDBM706244(US20240383893, Compound 110)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of ECD-His-tagged human recombinant ENPP1 using 2',3'-cGAMP as substrate preincubated with enzyme for 15 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 706244BDBM706244(US20240383893, Compound 110)
Affinity DataIC50: 2.20nMAssay Description:Preparation of 1×reaction solution: 50 mM Tris-HCl (pH 7.5), 10 mM NaCl, 0.5 mM CaCl2), 1 μM ZnCl2, 0.01% Tween-20, 0.01% BSA.Preparation of compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
US Patent