BDBM706417 US20240383900, Compound PPA-081

SMILES N#Cc1cnn2c(NCc3ccc(-c4ccccc4)cc3)cc(NC[C@H]3CCNC[C@@H]3O)nc12

InChI Key InChIKey=QNCCEVLQPYJWAB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706417   

TargetCyclin-dependent kinase 12(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM706417(US20240383900, Compound PPA-081)
Affinity DataIC50: 57nMAssay Description:A radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the two protein kinases (CDK12/CDK7). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM706417(US20240383900, Compound PPA-081)
Affinity DataIC50: 344nMAssay Description:A radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the two protein kinases (CDK12/CDK7). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent