BDBM706712 US20240383924, Compound 005

SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ccc4c(N5CC6C=CC(C5)N6)nc(OC[C@@]56CCCN5C[C@H](F)C6)nc4c3F)c12

InChI Key InChIKey=VCPLREZLJWOLBO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 706712   

TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706712(US20240383924, Compound 005)
Affinity DataIC50: 12.3nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent