BDBM706765 6-(1-(3-methyl-5- (trifluoromethyl)pyridin-2- yl)piperidin-4-yl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 7

SMILES Cc1cc(C(F)(F)F)cnc1N1CCC(N2CCC3(C2)CS(=O)(=O)C3)CC1

InChI Key InChIKey=UTHRXHADJKMDRZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706765   

LigandPNGBDBM706765(6-(1-(3-methyl-5- (trifluoromethyl)pyridin-2- yl)p...)
Affinity DataKi:  10nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
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LigandPNGBDBM706765(6-(1-(3-methyl-5- (trifluoromethyl)pyridin-2- yl)p...)
Affinity DataKi:  17.5nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent