BDBM706766 6-((1r,4r)-4-(1-isopropyl-3- (trifluoromethyl)-1H-pyrazol-5- yl)cyclohexyl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 8A

SMILES CC(C)n1nc(C(F)(F)F)cc1[C@H]1CC[C@H](N2CCC3(C2)CS(=O)(=O)C3)CC1

InChI Key InChIKey=BCBVPLXIKNGXLH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706766   

LigandPNGBDBM706766(6-((1r,4r)-4-(1-isopropyl-3- (trifluoromethyl)-1H-...)
Affinity DataKi:  16nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
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LigandPNGBDBM706766(6-((1r,4r)-4-(1-isopropyl-3- (trifluoromethyl)-1H-...)
Affinity DataKi:  34nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent