BDBM706771 6-((1R,3S)-3-(1-isopropyl-3- (trifluoromethyl)-1H-pyrazol-5- yl)cyclopentyl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 10B

SMILES CC(C)n1nc(C(F)(F)F)cc1[C@H]1CC[C@@H](N2CCC3(C2)CS(=O)(=O)C3)C1

InChI Key InChIKey=UMWARVLQJZFFCI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706771   

LigandPNGBDBM706771(6-((1R,3S)-3-(1-isopropyl-3- (trifluoromethyl)-1H-...)
Affinity DataKi:  19nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM706771(6-((1R,3S)-3-(1-isopropyl-3- (trifluoromethyl)-1H-...)
Affinity DataKi:  21.3nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent