BDBM706783 6-((1S,3S)-3-(1-isopropyl-3-(5- (trifluoromethyl)pyridin-3-yl)- 1H-pyrazol-5-yl)cyclopentyl)- 2-thia-6-azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 13D

SMILES CC(C)n1nc(-c2cncc(C(F)(F)F)c2)cc1[C@H]1CC[C@H](N2CCC3(C2)CS(=O)(=O)C3)C1

InChI Key InChIKey=OMKKJZHLVORLNY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706783   

LigandPNGBDBM706783(6-((1S,3S)-3-(1-isopropyl-3-(5- (trifluoromethyl)p...)
Affinity DataKi:  19nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM706783(6-((1S,3S)-3-(1-isopropyl-3-(5- (trifluoromethyl)p...)
Affinity DataKi:  71nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent