BDBM706806 (R)-6-(1-(4- (trifluoromethyl)phenyl)piperi- din-3-yl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 22A

SMILES O=S1(=O)CC2(CCN([C@@H]3CCCN(c4ccc(C(F)(F)F)cc4)C3)C2)C1

InChI Key InChIKey=OLACTUGDPOWMMY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706806   

LigandPNGBDBM706806((R)-6-(1-(4- (trifluoromethyl)phenyl)piperi- din-3...)
Affinity DataKi:  14nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM706806((R)-6-(1-(4- (trifluoromethyl)phenyl)piperi- din-3...)
Affinity DataKi:  34nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent