BDBM706810 6-((1r,4r)-4-(1-cyclobutyl-5- (trifluoromethyl)-1H-pyrazol-3- yl)cyclohexyl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 24

SMILES O=S1(=O)CC2(CCN([C@H]3CC[C@H](c4cc(C(F)(F)F)n(C5CCC5)n4)CC3)C2)C1

InChI Key InChIKey=DINNMSDGBWKIDD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706810   

LigandPNGBDBM706810(6-((1r,4r)-4-(1-cyclobutyl-5- (trifluoromethyl)-1H...)
Affinity DataKi:  11nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

LigandPNGBDBM706810(6-((1r,4r)-4-(1-cyclobutyl-5- (trifluoromethyl)-1H...)
Affinity DataKi:  28nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent