BDBM706814 (R)-7-((1r,4R)-4-(1-methyl-3- (trifluoromethyl)-1H-pyrazol-5- yl)cyclohexyl)-2-thia-7- azaspiro[4.5]decane 2,2-dioxide::US20240398781, Example 26B

SMILES Cn1nc(C(F)(F)F)cc1[C@H]1CC[C@H](N2CCC[C@]3(CCS(=O)(=O)C3)C2)CC1

InChI Key InChIKey=LABCBEOJRRGZDC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706814   

LigandPNGBDBM706814((R)-7-((1r,4R)-4-(1-methyl-3- (trifluoromethyl)-1H...)
Affinity DataKi:  12nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM706814((R)-7-((1r,4R)-4-(1-methyl-3- (trifluoromethyl)-1H...)
Affinity DataKi:  21nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent