BDBM706819 6-(1-(3-chloro-5- (trifluoromethyl)pyridin-2- yl)piperidin-4-yl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240398781, Example 30

SMILES O=S1(=O)CC2(CCN(C3CCN(c4ncc(C(F)(F)F)cc4Cl)CC3)C2)C1

InChI Key InChIKey=AHOXVUBWZDASLN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706819   

LigandPNGBDBM706819(6-(1-(3-chloro-5- (trifluoromethyl)pyridin-2- yl)p...)
Affinity DataKi:  13nMAssay Description:SPA: Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

LigandPNGBDBM706819(6-(1-(3-chloro-5- (trifluoromethyl)pyridin-2- yl)p...)
Affinity DataKi:  39nMAssay Description:DHCR7: The radioligand binding assay was prepared by adding assay buffer diluted hEBP-DHCR7 membrane at 66.7 μg/ml×150 μl/well into the 96-well compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent