BDBM707290 US12162878, Compound 213

SMILES [2H]C([2H])([2H])NS(=O)(=O)c5cnc(N1CCC2(CC1)CC2(F)F)c(c3cn(C)c(=O)c4CC=Cc34)c5

InChI Key InChIKey=GCDAPUPAGHUHLH-FIBGUPNXSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 707290   

TargetBromodomain-containing protein 2(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707290(US12162878, Compound 213)
Affinity DataIC50: 1.60nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707290(US12162878, Compound 213)
Affinity DataIC50: 4.10nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707290(US12162878, Compound 213)
Affinity DataIC50: 4.40nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707290(US12162878, Compound 213)
Affinity DataIC50: 15nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent