BDBM707293 US12162877, Compound Teriflunomide

SMILES C/C(O)=C(/C#N)C(=O)Nc1ccc(C(F)(F)F)cc1

InChI Key InChIKey=UTNUDOFZCWSZMS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707293   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery And Clinic

US Patent
LigandPNGBDBM707293(US12162877, Compound Teriflunomide)
Affinity DataIC50: 388nMAssay Description:Inhibitory activity was assessed by monitoring the reduction of 2,6-dichloroindophenol (DCIP), which is associated with the oxidation of dihydroorota...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent