BDBM707294 US12162878, Compound 202

SMILES CNS(=O)(=O)c5ccc(N1CCC2(CC1)CC2)c(c3cn(C)c(=O)c4CC=Cc34)c5

InChI Key InChIKey=VEPYYWIOIMZOLX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 707294   

TargetBromodomain-containing protein 2(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707294(US12162878, Compound 202)
Affinity DataIC50: 1.60nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707294(US12162878, Compound 202)
Affinity DataIC50: 4.5nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707294(US12162878, Compound 202)
Affinity DataIC50: 5.10nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM707294(US12162878, Compound 202)
Affinity DataIC50: 16nMAssay Description:The compounds were screened in vitro, and each compound was serially diluted to 10 concentrations. Four proteins BRD4 (D1+D2), BRDT (D1), BRD2 (D1+D2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent