BDBM707320 (R)-2-((2-Amino-7-(6-(pyrrolidin-1-ylmethyl)pyridin-3-yl)pyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol 2::US12162879, Example 2

SMILES CCCC[C@](C)(CO)Nc1nc(N)nc2cc(-c3ccc(CN4CCCC4)nc3)cnc12

InChI Key InChIKey=IPCMPAICJOWGSR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707320   

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707320((R)-2-((2-Amino-7-(6-(pyrrolidin-1-ylmethyl)pyridi...)
Affinity DataIC50: 2.70E+4nMAssay Description:Table 2: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS) (Shanghai Basalmedia Technologies Co., Ltd., B320, similarly her...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM707320((R)-2-((2-Amino-7-(6-(pyrrolidin-1-ylmethyl)pyridi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Table 3: I. Experimental Materials and Instruments1. Phosphate buffer solution (PBS);2. NADPH (Sigma N-1630);3. Human liver microsome (Corning Gentes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/21/2025
Entry Details
US Patent