BDBM708098 US12172992, Example 14

SMILES C[C@H]3CN(CCc2ccc(N1CCC(=O)NC1=O)cc2)CCN3c7ccc(Nc6cc(c5ccc([C@@H](C)NC(=O)c4nc(C(C)(C)C)no4)c(Cl)c5)ncn6)nc7

InChI Key InChIKey=DQWWVCQXTSHOSR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708098   

TargetTyrosine-protein kinase BTK(Human)
Abbvie

US Patent
LigandPNGBDBM708098(US12172992, Example 14)
Affinity DataIC50: 0.0530nMAssay Description:Btk kinase activity was measured in vitro using an electrophoretic mobility shift assay (MSA). The ability of Btk to phosphorylate a fluorescent pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent

TargetProtein cereblon(Human)
Abbvie

US Patent
LigandPNGBDBM708098(US12172992, Example 14)
Affinity DataIC50: 2.33E+3nMAssay Description:Competition Assay: Test compounds in 100% dimethyl sulfoxide were plated onto white, low volume 384 well plates (PerkinElmer Proxiplate 384 plus #600...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent