BDBM708444 3-amino-6-(((1-(2-(2,4- difluorophenyl)-2-hydroxy-3- (1H-1,2,4-triazol-1-yl)propyl)-2- methylpiperidin-4- yl)amino)methyl)-1-(4-phenyl- 3,4-dihydro-2H- benzo[b][1,4]oxazin-6- yl)thieno[2,3-b]pyrazin-2(1H)- one::US20240424113, Compound I-138

SMILES CC1CC(NCc2cc3c(nc(N)c(=O)n3-c3ccc4c(c3)N(c3ccccc3)CCO4)s2)CCN1CC(O)(Cn1cncn1)c1ccc(F)cc1F

InChI Key InChIKey=XVSNAHDDVCNVJP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708444   

TargetHeat shock protein 90 homolog(Yeast)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708444(3-amino-6-(((1-(2-(2,4- difluorophenyl)-2-hydroxy-...)
Affinity DataKd:  445nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent

TargetHeat shock protein 90(Neosartorya fumigata)
Bright Angel Therapeutics

US Patent
LigandPNGBDBM708444(3-amino-6-(((1-(2-(2,4- difluorophenyl)-2-hydroxy-...)
Affinity DataKd:  674nMAssay Description:Surface Plasmon Resonance (SPR) Experiments. SPR experiments were performed on a Biacore S200 instrument at 25° C. Biotinylated Hsp90 Nuclear Binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent