BDBM708479 (E)-N-[2-(4,6- dihydroxy-2- methoxy-3-methyl- benzoyl)-3,4- dihydro-1H- isoquinolin-7-yl]-4- (dimethylamino)-N- methyl-but-2-::US20240425453, Example 29

SMILES COc1c(C)c(O)cc(O)c1C(=O)N1CCc2ccc(N(C)C(=O)/C=C/CN(C)C)cc2C1

InChI Key InChIKey=QZFMIEQUBDZWMG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708479   

TargetMismatch repair endonuclease PMS2(Human)
Neophore

US Patent
LigandPNGBDBM708479((E)-N-[2-(4,6- dihydroxy-2- methoxy-3-methyl- benz...)
Affinity DataIC50: 550nMAssay Description:Test compounds, as 10 mM DMSO stocks, were dispensed into a Black Fluotrac 200 384 well medium binding plate (Greiner Bio-One, item number 781076) us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent