BDBM708517 3-(5-((2-(2-(2-(((2R,3as,5S, 6as)-hexahydro-2,5- methanopentalen-3a(1H)- yl)amino)ethoxy)ethoxy) ethyl)amino)-2-methyl-4- oxoquinazolin-3(4H)-yl) piperidine-2,6-dione::US20240425475, Compound GT-02497

SMILES Cc1nc2cccc(NCCCCCCCNC34CC5CC(CC3C5)C4)c2c(=O)n1C1CCC(=O)NC1=O

InChI Key InChIKey=YJWDUFGYXFIAFE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708517   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM708517(3-(5-((2-(2-(2-(((2R,3as,5S, 6as)-hexahydro-2,5- m...)
Affinity DataIC50: 660nMAssay Description:1. According to the instructions of the CEREBLON BINDING kits, the compounds to be tested of the present invention and lenalidomide were serially dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent