BDBM708520 3-(5-((2-(4-(4-((1s, 3s)-adamantan-1-yl) benzyl)piperazin- 1-yl)ethyl)thio)-2- methyl-4- oxoquinazolin-3(4H)- yl)piperidine-2,6-dione::US20240425475, Compound GT-03315

SMILES Cc1nc2cccc(SCCN3CCN(Cc4ccc(C56CC7CC(CC(C7)C5)C6)cc4)CC3)c2c(=O)n1C1CCC(=O)NC1=O

InChI Key InChIKey=HYBGNONHBFSJRT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708520   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM708520(3-(5-((2-(4-(4-((1s, 3s)-adamantan-1-yl) benzyl)pi...)
Affinity DataIC50: 1.98E+3nMAssay Description:1. According to the instructions of the CEREBLON BINDING kits, the compounds to be tested of the present invention and lenalidomide were serially dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent