BDBM708524 3-(5-((4-(((3r,5r,7r)- adamantan-1-yl) methyl)piperazin-1- yl)methyl)-2-methyl-4- oxoquinazolin-3(4H)- yl)piperidine-2,6-dione::US20240425475, Compound GT-03227

SMILES Cc1nc2cccc(CCCN3CCN(CCCNC45CC6CC(CC(C6)C4)C5)CC3)c2c(=O)n1C1CCC(=O)NC1=O

InChI Key InChIKey=QZVXQEXGIFUNNP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708524   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM708524(3-(5-((4-(((3r,5r,7r)- adamantan-1-yl) methyl)pipe...)
Affinity DataIC50: 2.24E+3nMAssay Description:1. According to the instructions of the CEREBLON BINDING kits, the compounds to be tested of the present invention and lenalidomide were serially dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent