BDBM708529 3-(5-(3-(4-(4-((3r,5r, 7r)-adamantan-1- yl)benzyl)piperazin-1- yl)prop-1-yn-1-yl)-2-methyl-4- oxoquinazolin-3(4H)- yl)piperidine-2,6-dione::US20240425475, Compound GT-03233

SMILES Cc1nc2cccc(C#CCN3CCN(Cc4ccc(C56CC7CC(CC(C7)C5)C6)cc4)CC3)c2c(=O)n1C1CCC(=O)NC1=O

InChI Key InChIKey=SMINYWQGVQLRLO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708529   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM708529(3-(5-(3-(4-(4-((3r,5r, 7r)-adamantan-1- yl)benzyl)...)
Affinity DataIC50: 2.24E+3nMAssay Description:1. According to the instructions of the CEREBLON BINDING kits, the compounds to be tested of the present invention and lenalidomide were serially dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent