BDBM708724 US20240425497, Example 52

SMILES O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C(F)(F)F)c3cc(CO)[nH]c3c2=O)c1)N1CC(F)C1

InChI Key InChIKey=GOITYANHHOBHOE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708724   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM708724(US20240425497, Example 52)
Affinity DataIC50: 100nMAssay Description:The assays were performed in assay buffer consisting of 20 mM Hepes, 150 mM NaCl, 0.01% Triton X-100, 0.5 mM TCEP, 0.01% BSA. On the day of the assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
US Patent